Valacyclovir given in a 5-day regimen of 500 mg twice per day is effective as short-term treatment of episodes of recurrent genital herpes. This study compared the efficacy of a shorter, 3-day course (for 402 patients) with that of a 5-day course (for 398 patients) of valacyclovir for persons with frequent recurrence of symptoms. No significant differences were detected between the 2 dosing schedules for any of the end points measured. Median times to lesion healing, of pain duration, and of episode length for the 5-day versus 3-day treatment were 4.7 versus 4.4 days, 2.5 days versus 2.9 days, and 4.4 days versus 4.3 days, respectively. The proportions of patients with aborted lesions were 26.6% and 25.4% in the 5-day and 3-day groups, respectively. A 3-day course of 500 mg of valacyclovir administered twice daily as episodic treatment of recurrent genital herpes is equivalent to a 5-day course with regard to key markers of efficacy. 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If you have herpes, it's extremely likely that you'll be prescribed either valacyclovir or a similar drug in order to manage the virus. Valacyclovir is highly effective in. Valaciclovir Tablets are used to treat genital herpes viral infections in adults. Since the virus reproduces very early in the infection, you will benefit most from treatment if you take Valaciclovir Tablets as soon as the first symptoms appear. Genital herpes is a viral infection caused by herpes simplex virus type 1 or 2. It causes blisters and burning or itching around the genitals, which may be painful. Valaciclovir is used to treat genital herpes infections in adults. People who have frequent episodes of genital herpes can also take Valaciclovir to help to prevent the attacks. If you suffer from six or more outbreaks a year suppression treatment may be suitable for you. Suppression treatment is taken everyday and helps to prevent recurrent outbreaks by 70-80% and can sometime prevent outbreaks all together. 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