Side Effects of Metformin can range from not so serious, all the way to deadly. Are the risks of Metformin and Glucophage side effects worth it? This page will give you information that might be able to help you decide that for yourself. Also known as Glucophage, this is an antidiabetic medicine most often used in those with Type 2 Diabetes who are also overweight. It’s also used extensively in women with Polycystic Ovarian Syndrome, a condition known as PCOS, which is often accompanied by higher blood sugar readings which often benefit from the blood sugar lowering effects of Metformin. 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Over the counter cough and cold remedies will often contain small amounts of iodine or stimulants (norepinephrine, neosynephrine, adrenaline etc) that may affect blood pressure and heart rate. Health food supplements containing kelp or seaweed extracts may contain substantial amounts of iodine which may also precipitate or exacerbate thyroid disease in susceptible persons. Many commonly used medications or supplements (iron, calcium, estrogen, proton pump inhibitors, statins) can cause alterations in thyroid hormone absorption or binding to plasma proteins, sometimes requiring dose adjustment of L-thyroxine iodine deficiency is no longer a problem, and individuals taking moderate or large amounts of iodine in the form of supplements may actually aggravate a pre-existing, or a latent predisposition to develop a thyroid condition. There continues to be enormous interest in the effects of supplements, nutrients and Vitamins on human health and thyroid function. 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