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    Letrozole is approved by the United States Food and Drug Administration (FDA) for the treatment of local or metastatic breast cancer that is hormone receptor positive or has an unknown receptor status in postmenopausal women. Tamoxifen is also used to treat hormonally-responsive breast cancer, but it does so by interfering with the estrogen receptor. However, letrozole is effective only in post-menopausal women, in whom estrogen is produced predominantly in peripheral tissues (i.e. in adipose tissue, like that of the breast) and a number of sites in the brain. In pre-menopausal women, the main source of estrogen is from the ovaries not the peripheral tissues, and letrozole is ineffective. In the BIG 1–98 Study, of post-menopausal women with hormonally-responsive breast cancer, letrozole reduced the recurrence of cancer, but did not change survival rate, compared to tamoxifen. Letrozole has been used for ovarian stimulation by fertility doctors since 2001 because it has fewer side-effects than clomiphene (Clomid) and less chance of multiple gestation. ) : Juego que se practica con un bate y una pelota entre 2 equipos de 9 jugadores, en un campo limitado por 4 almohadillas que marcan la carrera del jugador. Beef steak (Bistec) : loncha de carne, asada o frita. Blue Jeans: Pantalones de mesclilla Brother (hermano): Expresión que denota a un amigo. 5 Closet: Mueble con puertas utilizado para colgar vestimentas y guardar otros artículos de vestir Cell Phone: Telefono móvil Cool: expresión usada para denotar algo entretenido Corner: expresión utilizada en el soccer para demarcar una esquina o la salida del balón por una de las líneas de fondo. Copy: Copia Crazy: Loco Curso (course): evolución, ciclo Deleción (deletion): Eliminación. Business: Negocio Bye: Adios Car Wash: lavado de automobil CD: Disco compacto Chance: suerte, oportunidad, probabilidad. Deplecionar (deplete,to): disminuir, reducir o agotar. Drive in: Cine de autos Disket (disquete): unidad de almacenamiento de archivos computacionales. Chat: Conversación Cheese cake: Postre de queso Chequear (check, to): examinar, explorar, revisar. DVD: Disco de video digital Elicitar (elicit,to): provocar. Email: Mensaje electrónico enviado a través de la red computacional de Internet. Enfatizar (emphasize, to): destacar, insistir, recalcar, subrayar.

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