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    So many women with PCOS are prescribed Metformin (an insulin-sensitizing drug) to manage their Polycystic Ovarian Syndrome. Metformin has been shown to improve many aspects of PCOS, including weight loss, fertility and improved testosterone levels (1). But, it also leads to Vitamin B12 deficiency if used at high doses or for long periods of time. So, here’s what you need to know about Metformin and Vitamin B12 deficiency with PCOS. As I have already mentioned, Metformin is an insulin sensitizing drug that is often prescribed for women with PCOS. It works by decreasing absorption of glucose through the intestines, lowering the amount of glucose produced by the liver and making the body more sensitive to the insulin that is being produced. The overall effect of Metformin use for PCOS is lowered testosterone levels, improved ovulation and fertility as well as a more regular menstrual cycle. Well, it is good although there are some nasty side effects. A full discussion on Metformin is not going to be dealt with now, though. Metformin and Vitamin C interaction Treato - ciprofloxacin 500 uses Metformin and Vitamin c ascorbic acid drug Is it okay to take vitamin B complex if I take metformin? - Quora
     
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