But in those who develop joint pain, fatigue, nerve dysfunction, or fibromyalgia, symptoms can be treated with mild medications. A small percentage of people with Sjogren’s develop more severe inflammation, involving organs such as the kidneys, lungs, intestines, or brain. Hydroxychloroquine iris Chloroquine lethal dose Plaquenil is the brand name for the prescription drug hydroxychloroquine. It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Funny that your rheumy said plaquenil doesn’t work. It is for joint pain and fatigue and is a disease modifier that slows the progression. Its been a life saver for meespecially for lifting the fatigue. Autoimmune diseases, like rheumatoid arthritis and lupus, are linked. Facts for patients and caregivers about the DMARD drug Hydroxychloroquine Plaquenil such as usages, Today, it is used to treat rheumatoid arthritis, Discover the 5 Common Signs and Symptoms of Rheumatoid Arthritis. Your doctor may recommend artificial tears to ease the discomfort of dry eye syndrome. For these people, NYU Langone doctors may prescribe more aggressive medications. How does plaquenil work for sjogren's Sjogren's Syndrome Symptoms, Causes, Diagnosis, Treatment, Sjogrens and hormones - General - Sjogren's Syndrome Support Chloroquine transfection calcium phosphate We have a lot of members here who have never had positive blood work but had SjS confirmed through a biopsy. Plaquenil does not generally help with dryness issues, but is often prescribed to try to slow down the progression of the disease, and does help with inflammation caused by SjS e.g. joint pain and inflammation. Sjogren's diagnosis - prescribed Plaquenil?. How Does Plaquenil Work For Rheumatoid Arthritis. Medications for Sjogren’s Syndrome NYU Langone Health. Hi - I just started Plaquenil 400 mg a day two week ago and I started feeling less achy and tired a few days ago. Is it possible for it to work quicker in some people? I've heard it can take months, but I must say that I haven't felt like this since I was a kid - not achy or stiff. Has anyone had a similar I've heard that plaquenil does help w/ fatigue as well as the pain? Is this true. Right now I am not on any Dmards but when I push myself more than like 4 hrs a day out of the house running errands, etc I totally crash w/ fatigue and pain. I take tramadol and NSAIDs but wondering if I need. Hydroxychloroquine Plaquenil, a drug designed to treat malaria, is often helpful in treating Sjogren's syndrome. Drugs that suppress the immune system, such as methotrexate Trexall, also might be prescribed.