Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Chloroquine and furan 2 Chloroquine toxicity of retina On examination, a telltale sign of hydroxychloroquine toxicity is a bilateral change in the retinal pigment epithelium of the macula that gives the commonly described appearance of a bull’s-eye. This is a late finding, however, and too late for screening to be useful. I recently decided to stop taking Plaquenil because I was having constant chest pains even more so than I usually have due to Lupus. Since I have not taken it my chest feels so much better which is odd because chest pain is not listed as a side effect. Also I noticed that the Plaquenil I think was making me feel different but not in a good way. Plaquenil is a 6-weeker as far as the benefits are concerned, but it would be more dangerous to stop if you spend a lot of time outside and if this were the summer. If you're gonna experiment, I went off it cold turkey as it didn't hurt to do it that way, but you better get back on before the summer or you could experience a flare-up. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Stopping plaquenil change to what Stopping plaquenil - Sclero Forums MAIN - Sclero Forums, Had to stop taking Plaquenil - Hydroxychloroquine and tinnitusHydroxychloroquine brand name canadaPlaquenil prescribing informationHydroxychloroquine in lupus pregnancyMedication for prevention and treatment of chloroquine-resistant malaria I've had these visual disturbances---I don't know if stopping P will change anything, and I guess I'll find out. I have a feeling that Plaquenil takes quite awhile to leave your body. I will be thankful to get a break from my nightmares. I know that it's accumulating in my brain cells, and wonder if my retinas are next. Quitting Plaquenil after 2 years - Sjogren's World. What is the correct way to discontinue use of plaquenil?. Taking Plaquenil for Rheumatoid Arthritis. We can detect changes early enough to prevent any significant effect on vision, and stopping the medication at that point appears to halt progression of the changes.” Which annual screening tests to ask for “The message I want to get out is Pay a lot more attention to side effects of medication and any changes in vision,” Utterback says. Plaquenil isn a antiparasitic drug with anti-inflammatory affect. I have done a lot of research on this drug and haven't run into anybody who has complained of the withdrawal effect. Over the years on this site we have had quite a few people post that they didn't think that the plaquenil was working so they would stop taking it. For women, start with 100 pounds, and add 5 pounds for every inch over 5 feet. For men, start with 106 pounds, and add 6 pounds for every inch over 5 feet. The maximum dose of Plaquenil is 6.5 mg/kg of ideal body weight per day, regardless of whether a person is overweight, underweight, or normal weight.