Common causes include medications and the syndrome of inappropriate antidiuretic hormone (SIADH) secretion. Hyponatremia can be classified according to the volume status of the patient as hypovolemic, hypervolemic, or euvolemic. Generic plaquenil ingredients Why is hydroxychloroquine important in the treatment of lupus Plaquenil drug action Hyponatremia is commonly defined as a serum sodium concentration below 135 mEq/L, but the definition can vary to a small degree in different clinical laboratories 1,2. Most patients with hyponatremia have hypotonicity, but there are exceptions table 1. Hyponatremia without hypotonicity can occur in patients with hyperglycemia. Hyponatraemia is found among people who take Hydroxychloroquine sulfate, especially for people who are female, 60+ old also take medication Methotrexate, and have Breast cancer. This study is created by eHealthMe based on reports of 11,813 people who have side effects when taking Hydroxychloroquine sulfate from Food and Drug Administration FDA, and is updated regularly. Duloxetine is known to cause hyponatremia but stopping it didn’t matter. We’ll see. Sjogren’s can cause heart block as well, as can just plain aging. Anyway, per that link I posted the symptoms of even mild hyponatremia are somewhat surprising, including falls and attention issues. Differentiating between euvolemia and hypovolemia can be clinically difficult, but a useful investigative aid is measurement of plasma osmolality. Hypervolemic hyponatremia may be caused by congestive heart failure, liver cirrhosis, and renal disease. Plaquenil hyponatremia Hyponatremia in systemic lupus erythematosus patients., Hydroxychloroquine sulfate and Hyponatraemia - from FDA. Plaquenil eye exam recommendations Apr 27, 2019 Macrocytosis is a term used to describe red blood cells that are larger than normal. Also known as megalocytosis or macrocythemia, this condition typically causes no signs or symptoms and is usually detected incidentally on routine blood tests. Macrocytosis isn't a specific disease. Macrocytosis What causes it? - Mayo Clinic. Hyponatremia Mayo Clinic Connect. Hyponatremia - Causes, Pathophysiology, Algorithm.. Leukopenia, which frequently occurs in patients with systemic lupus erythematosus, is usually not severe i.e. white blood cell count of less than 1,000 × 10 3 per mm 3 1.0 × 10 9 per L and rarely requires treatment. Thrombocytopenia, if stable, and if the platelet count remains above 50,000 × 10 3 per mm 3. Hyponatremia is a condition where plasma sodium level falls to less than 135 mmol/L. The body maintains a careful balance of electrolytes like sodium, potassium and chloride within the cells as well as in fluid outside the cells like blood and body fluids. Sodium is necessary to carry out some important functions like maintaining blood pressure. Hyponatremia defined as a serum sodium level 134 mmol/L is the most common electrolyte abnormality in hospitalized patients. Certain drugs eg, diuretics, antidepressants, and antiepileptics have been implicated as established causes of either asymptomatic or symptomatic hyponatremia.