I currently take 6 tablets a week and I started taking them in February this year . Has anyone been through the same as me, and find that the meds simply haven't worked so you have to simply start again. I have called my nurse specialist but she hasn't got back yet. Hang in there- it's very early days x I'm afraid Jacki08 is right it's early days and these meds take time. I am still in a lot of pain I have immense fatigue and feel miserable. I started MTX in September along with naproxen and gradually built up to 8 tablets (20mg) a week by the end of December. Biaxin plaquenil lyme Plaquenil alcohol side effects Hydroxychloroquine anti inflammatory Starting plaquenil Medication Uses How To Use Side Effects Precautions Drug Interactions Overdose Notes Missed Dose Storage. USES Hydroxychloroquine is used to prevent or treat malaria infections caused by mosquito bites. It does not work against certain types of malaria chloroquine-resistant. Hi ya, I remember the frustration at the beginning, they started me on 8 tablets, didn't do much for 4 months so upped me to 10, after another 3-4 months it did start to help watch out for mouth ulcers, mine were horrendous, needed 6 x folic acid tablets a week to keep them at bay. Biologics Not Working Biologics Not Working - Next Steps When a Biologic Doesn't Help Your RA. Sometimes, biologic drugs will help you for a while and then don't work as well. It's not clear. Things have been in their stride since mid February and now it's looking good regarding fatigue, swelling and pain (though I only ever had a little pain compared to what others have described). I started taking mthx in October last year and expected results quite quickly. Hydroxychloroquine not working what next Hydroxychloroquine Oral Uses, Side Effects, Interactions., Methotrexate not working so what next? Hi everyone as. Plaquenil rash side effectsPlaquenil rash treatment What next if plaquenil doesn't work? Support Forums. I have to have liver and crp retest next week. My hair is coming out slightly Not in clumps are anything, just a little here or there. Really though in order not to have worse things happen it is what we have to do. I know it is scary but anything to stop the pain and misfunction of not. What next if plaquenil doesn't work?. If Your RA Biologic Doesn’t Help Enough What Next?. Plaquenil What You Need to Know - Kaleidoscope Fighting Lupus. It is licensed in the UK for the treatment of malaria. Hydroxychloroquine is particularly effective for systemic lupus erythematosus SLE and discoid lupus erythematosus DLE. By reducing inflammation, hydroxychloroquine can decrease pain, swelling and stiffness of joints, and improve or clear some rashes. Mar 17, 2016 If your overactive bladder medication isn’t working, don’t give up. Find out what other treatments you can explore. Share this article via email with one or more people using the form below. Dosage Hydroxychloroquine Plaquenil® is the drug of choice among antimalarials. Chloroquine is not commonly used because of greater toxicity on the eye. Chloroquine is not commonly used because of greater toxicity on the eye.