I am currently taking 200mg one time a day and my appetite has seriously decreased in the last two weeks. Just curious if anyone else had this as a side effect. Yes, Plaquenil causes both weight loss and loss of appetite. Hence, if the loss of appetite and weight loss started after you started on this drug, then yes, it could be due to Plaquenil. I was not losing weight or have a lack of appetite prior to Plaquenil so it must be the medicine. I personally had terrible nausea for almost 2 years when I was put on plaquinel, the nausea was the first symptom to leave....causing me to gain weight. I just find Im not as hungry as I was before, or that my appetite has changed. Days plaquenil to work Hydroxychloroquine and amoxicillin Weight loss is found among people who take Plaquenil, especially for people who are female, 50-59 old, have been taking the drug for 5 - 10 years, also take medication Enbrel, and have Pain. Side Effects Nausea, stomach cramps, loss of appetite, diarrhea, dizziness, or headache may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly. Remember. People taking Adderall for ADHD may experience weight loss due to the appetite suppression side effect even if they weren't trying to lose weight. According to a study published in 2013, most people who take Adderall non-medically give the reason of improving their productivity, with fewer saying they use it for weight loss. In this case, the cause of loss f appetite and weight loss has to be found. I was just curious if the medication was what caused my appetite to change or what. However, if you had loss of appetite and weight loss before your started this drug, then the drug can aggravate the process. At my last visit my Dr asked me if it had deminished my appetite so she is aware of it and the amount of weight I lost and is not concerned at this moment. I know diarhea is a common side affect of plaquinel. It wasn't that I was eating a lot, it was just that I was actually eating. I was on Prednisone for two months prior to Plaquenil and gained 18 lbs, so I needed to lose the weight anyway. Losing weight off of plaquenil Plaquenil - Uses, Side Effects, Interactions., Plaquenil Oral Uses, Side Effects, Interactions, Pictures. Is hydroxychloroquine an anti inflammatoryCan i take tamiflu with hydroxychloroquine So that's the update. The lesson here is - for those who need to go off plaquenil, be careful about just going off it cold turkey. Obviously some of CAN do that, but if you don't know if you're one of them - better to be on the safe side and wean slowly. Take it from me! I am feeling much better after bumping my dose back up over the last few. Let me tell you what weaning down from Plaquenil is like.. Turning to Adderall for Weight Loss - Verywell Mind. Rx Side Effects New Plaquenil Guidelines and More - American.. If experienced, these tend to have a Severe expression. Abnormal Liver Function Tests. Acute Liver Failure. Acute Pustular Eruptions On Skin. Bronchospasm. Decreased Blood Platelets. Decreased White Blood Cells. Deficiency Of Granulocytes A Type Of White Blood Cell. How to use Plaquenil. Lupus and/or rheumatoid arthritis patients will most likely take this medication by mouth, usually once or twice daily or as directed. Hydroxychloroquine generally is given to adults in doses of 200 mg or 400 mg per day. In some cases, higher doses can be used. Plaquenil caused some weight loss for me when I was on a higher dose. Now that I am on 200 mg. per day, I don't notice that anymore. Prednisone, on the other hand, has caused both a gain/loss, depending on the dosage.