Plaquenil is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. Free plaquenil Aralen dosage malaria prevention Hydroxychloroquine how long to take effect. Hi, i beleive Dmards can take up to 3 months to kick in so may take a bit longer to kick in. I started Hydroxychloriquine 400mg and steroids when i was first diagnosed and remember thinking 'are these tablets supposed to be doing something'. I think after about 2 weeks i felt a lot better but. I came across this page having the same question. How long does it take for Plaquenil to leave your system after discontinuing use. However, I do not want to stop taking it because of terrible side effects listed by other users of the med. I love this drug. I have never felt as good as I do now. Hi - I just started Plaquenil 400 mg a day two week ago and I started feeling less achy and tired a few days ago. Is it possible for it to work quicker in some people? I've heard it can take months, but I must say that I haven't felt like this since I was a kid - not achy or stiff. Has anyone had a similar Plaquenil is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. This medicine is not effective against all strains of malaria. How long does it take for plaquenil to kick in Lupus Medicines Hydroxychloroquine - Brigham and Women's Hospital, How long does it take for plaquenil to leave your system? Plaquenil with percocetPlaquenil and acneSickle cell disease hydroxychloroquine thrombosisChloroquine resistance map malaria Flesh colored itchy rash on top of feet and inside ankle. I do take plaquenil hydroxychloroquine 400mg daily fo more Flesh colored itchy rash on top of feet and inside ankle. I do take plaquenil hydroxychloroquine 400mg daily for ra. Havent changed soaps, detergents, etc. How long does it take for plaquenil hydroxychloroquine to.. Immune & Autoimmune - Lupus Plaquenil - Can It Work Quickly?. Plaquenil -. BTW, a great resource for medication questions is your Pharmacist. If you look up the "half life" of Plaquenil on the internet, you will find it does stay in your system for quite a while, as long as 2-3 months. Of course, its concentration decreases every day. From my point of view I have had less pain in my legs at night and the fatigue isn’t as bad. My rash is now coming and going rather than staying. But it is t perfect yet and may never be but inflammation specifically if experienced for a long period of time changes how cells behave and this can take a long time to reverse and may never fully. She said we could try Plaquenil - a milder drug. I was told it takes two months before patients feel any improvement, it took little less for the drug to kick in. Now, it's been a year - I have no flares, no pain and no side effects I can think of. I take one pill in the morning, one in the evening. This drug works well for me."