This medicine is also sometimes given off-label to help the following conditions: Also, let your doctor know if you drink large amounts of alcohol before starting on this medicine. Your doctor will probably want to order frequent tests to check your body's response to chloroquine. Plaquenil and risperidone Plaquenil heartburn Signs of a severe allergic reaction, which may include hives, rash, itching, difficulty breathing, tightness in the chest, or swelling of the face, mouth, lips, or tongue Back to Top Chloroquine. Doctors give trusted answers on uses, effects, side-effects, and cautions Dr. Fowler on chloroquine alternatives Chloroquine is an anti-malarial medication, it is meant to be taken by prescription only. It does have some side effects, but at standard, recommended doses it is usually well tolerated. In the Leprosy Research Department of the School of Tropical Medicine, Calcutta, the authors were interested by a report by BRUCE-CHWATT and HORN this Bulletin, 1959, v. 56, 120 that in 500 patients kept on pyrimethamine prophylaxis for a year the incidence of lepra reactions was reduced. Let your healthcare provider know if your symptoms either don't improve or worsen while taking this medicine. Keep all appointments with your doctor and laboratory. Chloroquine in lepra reaction Lepra Reaction And Erythma Nodosum Leprosum -, Chloroquine alternatives - Answers on HealthTap Chloroquine and breastfeedingPain when stopping hydroxychloroquine plaquenilChloroquine and prime Without treatment, type 2 lepra reactions continue for about 2 weeks then settle down. Recurrences are frequent. Untreated type 2 lepra reactions can result in renal failure requiring dialysis, liver failure requiring transplantation, blindness, and/or long-term inflammation of the testicles. Lucio phenomenon Lepra reactions DermNet NZ. Chloroquine for Reactions in Leprosy.. Chloroquine Oral Uses, Side Effects, Interactions, Pictures.. Leprosy reactions mainly encountered are type 1 and type 2 lepra reactions. Type 2 lepra reaction, otherwise termed erythema nodosum leprosum, is an acute inflammatory reaction seen in patients with lepromatous leprosy or occasionally in borderline lepromatous leprosy. Rarely in severe type 2 leprosy reaction nodular lesions breakdown to form. The mention of Chloroquine popular malaria drug as a possible cure for the virus has sparked different reactions from internet users. @BhadmusAkeem It is interesting to know that Chloroquine phosphate that used to itch our body back in those days, has proven effective in treating coronavirus #COVID19 and shows positive clinical effects. From these results it is concluded that chloroquine is useful in controlling lepra reaction and particularly useful because of the ease of administration and low toxicity. It is at least worthy of further trial.