This medicine is also sometimes given off-label to help the following conditions: Also, let your doctor know if you drink large amounts of alcohol before starting on this medicine. Your doctor will probably want to order frequent tests to check your body's response to chloroquine. Plaquenil for rheumatoid arthritis treatment Plaquenil for seronegative arthropathy Plaquenil white hair Plaquenil hypercalcemia The dose of Chloroquine that you are given will depend on why you're using it. If you're using Chloroquine to prevent Malaria, the most common dosage is 300mg-500mg of chloroquine once a week. Take the tablets after a meal and start taking them at least one week before entering the Malaria-infected area. The dosage used for rheumatoid arthritis and other inflammatory diseases is small compared to that used for cancer. Typically, people with rheumatoid arthritis are initially prescribed three 2.5 milligram methotrexate pills 7.5 milligrams total to be taken together once weekly, on the same day of the week e.g. every Saturday. Rheumatoid arthritis is a chronic disorder for which there is no known cure. Fortunately in the last few years, a shift in strategy toward the earlier institution of disease modifying drugs and the availability of new classes of medications have greatly improved the outcomes that can be expected by most patients. Let your healthcare provider know if your symptoms either don't improve or worsen while taking this medicine. Keep all appointments with your doctor and laboratory. Chloroquine dose in rheumatoid arthritis RA and Hydroxychloroquine How Effective is it for Rheumatoid., Methotrexate Dosage for Rheumatoid Arthritis - Why Weekly? Chloroquine antidoteChloroquine as antiamoebicChloroquine phosphate tablets ip 500mg The effect of long-term 18–70 months chloroquine treatment 250 mg daily, in rheumatoid arthritis RA was studied in 20 patients. Sedimentation rates were significantly reduced, as compared to a reference group of 10 RA patients on no treatment of disease modifying anti-rheumatic drugs. Radiographical progression of the disease was low in the majority of chloroquine-treated patients but. Chloroquine in long-term treatment of rheumatoid arthritis.. Rheumatoid Arthritis Treatment Options Johns Hopkins.. Chloroquine MedlinePlus Drug Information. Dosage for rheumatoid arthritis. Adult dosage ages 18 years and older Typical starting dosage 400–600 mg per day, given as a single daily dose or in two 2 divided doses. Chloroquine retinopathy in patients with rheumatoid arthritis. Elman A, Gullberg R, Nilsson E, Rendahl I, Wachtmeister L. 270 consecutive patients with rheumatoid arthritis who had received chloroquine therapy were examined ophthalmologically for toxic retinal lesions. The total annual dose of chloroquine was 70-75 g. Usual Adult Dose for Malaria Prophylaxis. 500 mg chloroquine phosphate 300 mg base orally on the same day each week Comments-If possible, suppressive therapy should start 2 weeks prior to exposure; if unable to start 2 weeks before exposure, an initial loading dose of 1 g chloroquine phosphate 600 mg base may be taken orally in 2 divided doses, 6 hours apart.