They are most common among people with weak immune systems. People with certain health conditions may need to take medications with side effects that can weaken your immune system and put you at risk for fungal infections. Hydroxychloroquine eye symptoms Chloroquine and proguanil dose They use plaquenil to suppress your immune system to slow it down, not speed it up. Your system is working overtime, so IMO, its stronger and that causes the problems we have the body needs a nice nuetral immune system working normally. My gyn oncologist was concerned that the Plaquenil may affect my immune system to ward of the hpv since we all know a good immune system is needed to fight the virus --- He understands the RA pain conundrum I have. These medications may also prevent lupus from spreading to certain organs, such as the kidney and central nervous system your brain and spinal cord and may help to reduce flares by as much as 50%. Plaquenil and other anti-malarials are the key to controlling lupus long term, and some lupus patients may be on Plaquenil for the rest of their lives. Fungal infections can range from mild to life-threatening. Specifically, corticosteroids and TNF (tumor necrosis factor) inhibitors are two types of medications that can increase your chances of getting a fungal infection. Does plaquenil suppress the immune system Anyone on Hydroxychloroquine plaquenil - Autoimmune., Plaquenil and its affect on the immune system DailyStrength Chloroquine hemazoinNon aqueous titration of chloroquine phosphate I've been on 400 mg plaquenil since last Dec 2007. My symptoms have been under the control. Some literatures recommended not to take this medicine while on AP. Others seemed to not worry about it. Interesting thing is “Plaquenil is an anti parasite medicine developed to treat malaria. Plaquenil - Road Back Foundation. Treating Lupus with Anti-Malarial Drugs Johns Hopkins Lupus.. Plaquenil. This action suppresses the normally overactive immune response in lupus patients which may explain one reason Plaquenil works so well for those suffering with lupus. Plaquenil is a slow-acting drug, meaning that it can take up to 6 months to experience the full benefits of this medication, but it is possible for symptoms to improve in as few as 1 or 2 months. Summary. Hydroxychloroquine Plaquenil is a drug that is classified as an anti-malarial drug. Plaquenil is prescribed for the treatment or prevention of malaria. It is also prescribed for the treatment of rheumatoid arthritis, lupus, and the side effects of lupus such as hair loss, joint pain, and more. The way I've always understood it, Plaquenil is NOT a immunosupressant. Immunopressant's are meds that suppress the immune system.prednisone.drug suppresses our immune system, calms it down so that our psycho immune system won't turn around and attack us so much.