I'm interested to eventually see the mechanism by which COVID19 is causing pneumonia. It would be an additional effect as well as this would not play a role in cell culture. My guess for the pneumonia is the cytokine induction induced by viral RNA or other innate immune signals. Hydroxychloroquine side effects vision Starting plaquenil Multinational and local drugmakers are speeding up manufacturing and supply of chloroquine phosphate after the anti-malarial drug was included in the latest version of treatment guidelines for novel coronavirus pneumonia by the National Health Commission. The commission on Wednesday issued the sixth version of its diagnosis and treatment plan for the novel coronavirus to include Large chloroquine overdoses are almost inevitably fatal. We describe the presentation and management of a patient with such an overdose who survived, due to general supportive care and new specific treatment. Chloroquine, a well-known anti-malarial drug may be lethal when ingested in large amount. We report the case of a 45 year-old patient who ingested 10 g of chloroquine in a suicidal attempt, 3 h prior to presentation. Despite aggressive management, There might be a source for coronavirus-induced cell death out there ... Another option is induced cell death by virus infection. Chloroquine phosphate lethal Antiviral Activity of Chloroquine against Human Coronavirus OC43., Massive chloroquine overdose--a survivor. Plaquenil eye octPlaquenil assistance programRestarting plaquenil CHLOROQUINE PHOSPHATE, USP DESCRIPTION ARALEN, chloroquine phosphate, USP, is a 4-aminoquinoline compound for oral administration. It is a white, odorless, bitter tasting, crystalline substance, freely soluble in water. ARALEN is an antimalarial and amebicidal drug. CHLOROQUINE PHOSPHATE, USP. PDF Chloroquine overdose Hugues Lefort and Olga Maurin.. Chloroquine drug Britannica. Precautions and Warnings With Chloroquine Let your healthcare provider know if you have any medical issues, such as psoriasis, alcoholism, or kidney disease, before taking chloroquine. Precautions and warnings with this drug also apply to people who have certain allergies and women who are pregnant or breastfeeding. Jun 08, 2009 Antiviral activity of chloroquine against a lethal HCoV-OC43 infection in newborn C57BL/6 mice. We investigated whether chloroquine could prevent death in newborn mice as a result of infection with HCoV-OC43. C57BL/6 mice were selected in view of their susceptibility to HCoV-OC43 14, 15. Pregnant mice were left untreated or treated. What threatened to be a very dark period for the world, both medically and economically, has finally seen a ray of light. Recent reports state that anti-malarial drug chloroquine phosphate could play a key role in battling the deadly novel coronavirus, now called Covid-19.