It may have both an anti-spirochaete activity and an anti-inflammatory activity, similar to the treatment of rheumatoid arthritis. And caution is required if patients have certain heart conditions, diabetes, psoriasis etc. Drug store hydroxychloroquine Drug innteraction of adderall with plaquenil Chloroquine in lepra reaction PLAQUENIL prolongs the QT interval and should not be administered with other drugs that have the potential to induce cardiac arrhythmias. Also, there may be an increased risk of inducing ventricular arrhythmias if PLAQUENIL is used concomitantly with other arrhythmogenic drugs. Urinary excretion in cases of both overdosage and sensitivity. Actions Like chloroquine phosphate, USP, PLAQUENIL is highly active against the erythrocytic forms of P. vivax and malariae and most strains of P. falciparum but not the gametocytes of P. falciparum. PLAQUENIL does not prevent relapses in patients with vivax or malariae malaria Hydroxychloroquine is a 4-aminoquinoline derivative prepared by beta hydroxylation of chloroquine. It is used in the treatment of malaria, rheumatoid arthritis, and lupus erythematosus, and marketed under the name Plaquenil Sanofi Pharmaceuticals, New York, NY. The most serious adverse effects affect the eye, with dose-related retinopathy as a concern even after hydroxychloroquine use is discontinued. The most common adverse effects are a mild nausea and occasional stomach cramps with mild diarrhea. Plaquenil excretion PLAQUENIL HYDROXYCHLOROQUINE SULFATE, USP WARNING., PLAQUENIL® - Food and Drug Administration Plaquenil dosage for psoriatic arthritisChloroquine drug actionDying hair while taking plaquenilPlaquenil eye toxicity PLAQUENIL is indicated for the treatment of chronic discoid lupus erythematosus and systemic lupus erythematosus in adults. Rheumatoid Arthritis. PLAQUENIL is indicated for the treatment of acute and chronic rheumatoid arthritis in adults. CONTRAINDICATIONS. Use of PLAQUENIL is contraindicated in patients with known hypersensitivity to 4 PLAQUENIL HYDROXYCHLOROQUINE SULFATE TABLETS, USP DESCRIPTION. Treatment of hydroxychloroquine overdose - ScienceDirect. Plaquenil Oral Uses, Side Effects, Interactions.. Hydroxychloroquine Plaquenil is used to treat malaria, lupus, and rheumatoid arthritis. Learn about side effects, warnings, dosage, and more. What is Plaquenil used for Rheumatoid arthritis. Rheumatoid arthritis is a form of arthritis with inflammation of the joints. Systemic Lupus Erythematous SLE SLE is a disease in which a person's normal immunity is upset. Discoid Lupus Erythematous DLE DLE is similar to SLE except it only. The long half-life can be attributed to extensive tissue uptake rather than through decreased excretion. Peak plasma levels of hydroxychloroquine were seen in about 3 to 4 hours. Renal clearance in rheumatoid arthritis RA patients taking Plaquenil for at least six months seemed to be similar to that of the single dose studies in volunteers, suggesting that no change occurs with chronic dosing.