Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Plaquenil trackid sp-006 Hydroxychloroquine gingival hyperplasia Plaquenil and vaccines Plaquenil and valium Conclusion. Patients and their physicians prescribing hydroxychloroquine need to be keenly aware of retinal toxicity risks and the importance of regular screening, and ophthalmologists who see these patients should keep retinal toxicity in the front of their minds. Risk is most accurately assessed on the basis of duration of use relative to daily dose/body weight Marmor AAO 2016; Melles 2014. Based on these risks, the American Academy of Ophthalmology AAO recommends not exceeding a daily hydroxychloroquine dosage of 5 mg/kg using actual body weight in most patients. Previous recommendations to use. This may lead to lasting eyesight problems. The risk may be higher if you have some types of eye or kidney problems. The risk may also be higher with some doses of hydroxychloroquine, if you use hydroxychloroquine for longer than 5 years, or if you take certain other drugs like tamoxifen. Call your doctor right away if you have any eyesight. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Omphthamologists risks of hydroxychloroquine Hydroxychloroquine-Induced Retinal Toxicity - American., Hydroxychloroquine Professional Patient Advice - Can i take claritin with plaquenilHow long do you take chloroquineCost of plaquenil in usAct or chloroquine malariaDoes plaquenil lower your immune system Hydroxychloroquine-related eye problems were once considered rare, but better detection methods now show that they occur in about 7 percent of patients. The risk increases with a higher dose and longer therapy. Vision risks. Hydroxychloroquine is dosed according to body weight. Wrong Hydroxychloroquine Dose Is Common, Putting Eyes at Risk. Hydroxychloroquine Indications, Side Effects, Warnings.. Hydroxychloroquine toxicity - EyeWiki. To determine the prevalence of high-risk factors for hydroxychloroquine HCQ retinopathy and compliance with the American Academy of Ophthalmology AAO screening guidelines at the San Francisco Veterans Affairs Medical Center VASF and to develop an approach to improve the risk-benefit relationship and informed consent during HCQ treatment. If you are taking Plaquenil to treat an inflammatory condition or malaria, you should be aware of the side effects that may occur to your eyes and vision. Plaquenil hydroxychloroquine is in a class of drugs called disease-modifying anti-rheumatic drugs, which are used to decrease inflammation, pain and joint damage. Because HCQ is cleared by the kidneys, renal disease raises the risk of toxicity, and both dosage and screening frequency may need to be adjusted in these patients.2. Tamoxifen use. Concomitant use of HCQ and tamoxifen, which is prescribed to treat and prevent breast cancer, raises the risk of HCQ toxicity approximately 5-fold.