Malaria is common in areas such as Africa, South America, and Southern Asia. This medicine is not effective against all strains of malaria. Chloroquine treatment malaria What happens if you take too much hydroxychloroquine Can you take hydroxychloroquine sulfate if youre allergic to.sulfa A similar study from earlier this year shows Plaquenil can, in fact, address pneumonia. 5 Specifically, it’s been used to reduce the risk of pneumocystis pneumonia in lupus patients. 5 Plaquenil is commonly used in rheumatoid arthritis, but was originally developed as an antimalarial medication. Substitutes and alternatives to Plaquenil hydroxychloroquine for uses like Rheumatoid arthritis, Lupus and Malaria Plaquenil hydroxychloroquine Alternatives & Similar Drugs - Skip to full site navigation Hydroxychloroquine, sold under the brand name Plaquenil among others, is a medication used for the prevention and treatment of certain types of malaria. Specifically it is used for chloroquine-sensitive malaria. Other uses include treatment of rheumatoid arthritis, lupus, and porphyria cutanea tarda. It is taken by mouth. Common side effects include vomiting, headache, changes in vision and muscle weakness. Severe side effects may include allergic reactions. It does not appear to be safe during Taking hydroxychloroquine long-term or at high doses may cause irreversible damage to the retina of your eye. Hydroxychloroquine is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Medication similar to plaquenil Plaquenil hydroxychloroquine Alternatives & Similar., Plaquenil hydroxychloroquine Alternatives & Similar Drugs. Lysosomotropic agent chloroquine I "know" I need some meds, but cannot tolerate Plaquenil. Wondering if anyone has come across something "natural" that mimics it. Thanks & LIGHT*****carole - Hi, Carole. When I started Plaquenil, my GI system was in an uproar. But it usually was anyway. I didn't realize, until I saw Dr. Natural" alternative to Plaquenil. - HealthBoards. Hydroxychloroquine - Wikipedia. Plaquenil Uses, Dosage & Side Effects -. Drugs That Prolong QT Interval And Other Arrhythmogenic Drugs. PLAQUENIL prolongs the QT interval and should not be administered with other drugs that have the potential to induce cardiac arrhythmias. Also, there may be an increased risk of inducing ventricular arrhythmias if PLAQUENIL is used concomitantly with other arrhythmogenic drugs. Compare Plaquenil head-to-head with other drugs for uses, ratings, cost, side effects, interactions and more. Plaquenil rated 6.8/10 in overall patient satisfaction. Plaquenil Compared to Alternatives - Hydroxychloroquine Plaquenil is considered a disease-modifying anti-rheumatic drug DMARD. It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria.