Hydroxychloroquine is available as the brand-name drug Plaquenil. Generic drugs usually cost less than the brand-name version. Hydroxychloroquine may be used as part of a combination therapy. Hydroxychloroquine quinine Plaquenil age spots Methotrexate sodium oral brand names and other generic formulations include Methotrexate Anti-Rheumatic Oral, Rheumatrex Oral, Trexall Oral All generic drug interactions for methotrexate sodium oral lists will include brand and generic names OBJECTIVE To examine the bioavailability of methotrexate MTX in the presence of hydroxychloroquine HCQ, and vice versa, to determine a possible pharmacokinetic explanation for the observation that combination treatment of rheumatoid arthritis with MTX and HCQ has been shown, clinically, to be more potent than MTX used alone. Taking Folic Acid with Methotrexate for Arthritis 9 Things You Must Know This supplement can help minimize many bothersome side effects from MTX. Methotrexate is the leading disease-modifying anti-rheumatic drug DMARD given to people with rheumatoid arthritis RA and many other types of inflammatory arthritis. Hydroxychloroquine is used to treat lupus erythematosus and rheumatoid arthritis. It isn’t fully understood how this drug works to treat lupus erythematosus or rheumatoid arthritis. That means you may need to take it with other drugs. It treats malaria by killing the parasites that cause the disease. Can you take hydroxychloroquine with methotrexate RA and Hydroxychloroquine How Effective is it for., Combination therapy with methotrexate and. Plaquenil chplPlaquenil c 24-2Side effects of plaquenil pmsBest time to take plaquenil Over the long term hydroxychloroquine can reduce pain, swelling and joint stiffness. If you have lupus, it may also improve the rash. It may be as long as 12 weeks before you notice the benefits. Hydroxychloroquine is often taken in combination with other drugs such as methotrexate. Hydroxychloroquine Side-effects, uses, time to work. Taking Folic Acid with Methotrexate What Patients Need to Know. Treatment of Rheumatoid Arthritis with Methotrexate Alone.. This study is created by eHealthMe based on reports of 5,663 people who take Hydroxychloroquine sulfate and Methotrexate from Food and Drug Administration FDA, and is updated regularly. On eHealthMe, you can evaluate side effects and drug interactions from 16 million FDA reports. The results are personalized to your gender and age 0-99+. Cellophanemanghost, I believe you are right about taking into consideration of a person's build, my doc started doing that for me when I was on methotrexate during my second month on it. As for my dealing with plaquenil, I noticed some changes about being able to move with out too much pain in the first 8-10 hours. Medicines that impair kidney function can increase levels of methotrexate in the body. Taking these medicines in combination with methotrexate increases the risk of bone marrow suppression.