What is chloroquine resistance

Discussion in 'Generic Chloroquine Online' started by starmajor, 20-Mar-2020.

  1. rdmaster Well-Known Member

    What is chloroquine resistance


    Parasites that cause malaria typically enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia.

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    Chloroquine is an antimalarial. It is used to prevent malaria and it is also used as a treatment for acute malaria. Chloroquine by itself is not recommended anymore due to the widespread resistance to it. Therefore, chloroquine is now used in combination with proguanil for travel to certain countries. Chloroquine is the prototype anti malarial drug, most widely used to treat all types of malaria except for disease caused by chloroquine resistant Plasmodium falciparum. It is highly effective against erythrocytic forms of Plasmodium vivax, Plasmodium ovale and Plasmodium malariae, sensitive strains of Plasmodium falciparum and gametocytes of Plasmodium vivax. Chloroquine Phosphate, USP, is a 4-aminoquinoline compound for oral administration. It is a white, odorless, bitter tasting, crystalline substance, freely soluble in water. Chloroquine Phosphate Tablets are an antimalarial and amebicidal drug.

    Chloroquine is also used to treat amebiasis (infection caused by amoebae). Chloroquine is used to treat and to prevent malaria.

    What is chloroquine resistance

    Chloroquine drug Britannica, Chloroquine C18H26ClN3 - PubChem

  2. Chloroquine pink1
  3. Chloroquine is a medication used to prevent and to treat malaria in areas where malaria is known to be sensitive to its effects. Certain types of malaria, resistant strains, and complicated cases typically require different or additional medication.

    • Chloroquine - Wikipedia.
    • CHLOROQUINE PHOSPHATE TABLETS, USP 250 MG and 500 MG.
    • Aralen chloroquine Malaria Drug Side Effects & Dosage.

    Chloroquine resistance is widespread and, at present, is particularly prominent in various parts of the world including sub- Saharan Africa, Southeast Asia, the Indian subcontinent, and over large portions of South America, including the Amazon basin 1. Chloroquine became the drug of first choice in malaria therapy for more than two decades until resistance limited the use of the drug. The resistance is correlated to point mutations in the gene pfcrt 26. The gene codes for a transporter PfCRT. Subsequently, chloroquine resistant P. falciparum probably arose in four separate locations starting with the Thai-Cambodian border around 1957; in Venezuela and parts of Colombia around 1960; in Papua New Guinea in the mid-1970s and in Africa starting in 1978 in Kenya and Tanzania and spreading by 1983 to Sudan, Uganda, Zambia and Malawi.

     
  4. antlog Moderator

    Chloroquine is the generic form of the brand-name prescription medicine Aralen, which is used to prevent and treat malaria — a mosquito-borne disease caused by a parasite — and to treat amebiasis, an infection of the intestines caused by a parasite. Malaria - Chapter 4 - 2020 Yellow Book Travelers' Health. Medicines for the Prevention of Malaria While Traveling. Primaquine - FDA prescribing information, side effects and uses
     
  5. Garry56 User

    Hydroxychloroquine is used to prevent or treat malaria infections caused by mosquito bites. Vertigo and Lupus Dr Garys Lupus Treatment System Cure & Relief Plaquenil and vertigo ProHealth Fibromyalgia, ME/CFS and. Plaquenil Hydroxychloroquine - Side Effects, Dosage.
     
  6. pimc Well-Known Member

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