Is prednisone and plaquenil safe during pregnancy

Discussion in 'Discount Prescription Drugs From Canada' started by AleZver, 21-Feb-2020.

  1. Jet-Black XenForo Moderator

    Is prednisone and plaquenil safe during pregnancy


    -The short-term use of corticosteroids antepartum for the prevention of respiratory distress syndrome does not seem to pose a risk to the fetus or newborn infant. Teratogenicity including increased incidence of cleft palate have occurred in animal studies.

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    The evidence to date regarding corticosteroid exposure in pregnancy and select pregnancy and birth outcomes is limited and inconsistent. Here we provide a narrative review of published literature summarizing the findings for oral clefts, preterm birth, birth weight, preeclampsia and gestational diabetes mellitus. The use of HCQ during pregnancy has long been debated, but nowadays, consensus is reached that it is safe and it is frequently prescribed during pregnancy to diminish flares 2, 3. However, reports on the detailed effects of HCQ on pregnancy outcomes are scarce and mostly focus on teratogenicity. Even though the symptoms of RA may improve for many women during pregnancy, many pregnant women with RA may still need to use pain control medications and medications to control inflammation. While the safest course of action is to avoid use of all drugs during pregnancy, this may not be possible.

    Reduced placental and birth weight have been recorded in animals and humans after long term treatment. A number of cohort and case controlled studies in humans suggest maternal corticosteroid use in the first trimester produces a slight increased risk of cleft lip with or without cleft palate (increased from 1 out of 1000 to 3 to 5 out of 1000 infants).

    Is prednisone and plaquenil safe during pregnancy

    Lupus and Pregnancy Tips for Living with Lupus While Pregnant, Hydroxychloroquine Use in Lupus Patients during Pregnancy.

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  4. I started with plaquenil last year, yes it took almost 6 months to get a level in your body, it does help, trust me. I was on Prednisone 7.5 to 10 mg per day, had a bad flair up and I am on 40 mg per day, last Friday the dr.''s told me to go down by 5 mg per week, so from 40mg to 35 mg per day.

    • Prednisone and Plaquenil question" Lupus Community..
    • Drug Safety in Pregnant & Nursing Women.
    • Pregnancy and Plaquenil - HealthBoards.

    My rheumatologist prescribed me Plaquenil, he’s assured me it’s safe during pregnancy and I plan to contact my OB tomorrow to get her thoughts. I’m just so anxious because I want the pain to go away and enjoy my pregnancy as much as one can but I also don’t want to do anything at all to harm my unborn baby. Despite these risks, corticosteroids are considered relatively safe throughout pregnancy when given at low doses below 15 mg/day. They should be avoided, if possible, during the first trimester, when risk for defects of the hard palate are highest. I get really bad flare ups and prednisone 10 mg is the only thing that helps settle it. I have talked to my OB and she said to only take it when necessary so I'm doing that. I have taken it a handful of times over this pregnancy. Does anyone else have experience taking it while pregnant?

     
  5. lehaoper Guest

    Chloroquine has long been used in the treatment or prevention of malaria from Plasmodium vivax, P. malariae, excluding the malaria parasite Plasmodium falciparum, for it started to develop widespread resistance to it. Chloroquine Dosage Guide with Precautions - Malaria drug chloroquine potential treatment for coronavirus Malaria - Diagnosis and treatment - Mayo Clinic
     
  6. ReKiL XenForo Moderator

    Chloroquine Phosphate – Marine Fish Diseases and Treatment Chloroquine Phosphate. In most cases, 250 mg tablets have an equivalence of 150 mg chloroquine base, and 500 mg tablets have an equivalence of 300 mg chloroquine base. Although the purity mentioned above is generally accurate, it would be best to verify the chloroquine base contained in the tablets of your choice in order to be able to.

    Chloroquine Dosage Guide with Precautions -