It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Malaria is spread by mosquitoes, which transmit the parasites that cause the infection, usually in tropical and subtropical parts of the world. Side effects discontinuing plaquenil Plaquenil cold urticaria You take Plaquenil as a pill 1 or 2 times a day. Take the pills with food or milk. Your body weight will tell your doctor what dose is safe for you. You should not take this medicine if you already have problems with the retinas in your eyes. You should not take this if you have an allergy to antimalarial medications. You should always take your anti-malarial medications with food to prevent stomach upset. If a stomachache does occur, it is usually temporary. However, if you experience stomach upset while taking generic hydroxychloroquine, ask your doctor about trying name-brand Plaquenil instead. Hydroxychloroquine oral tablet can interact with other medications, vitamins, or herbs you may be taking. An interaction is when a substance changes the way a drug works. For example, it may be combined with an antibiotic to treat chronic Q-fever, which humans usually catch from farm animals or raw milk. Plaquenil is used to treat other types of infections too. When should you take hydroxychloroquine Hydroxychloroquine Side-effects, uses, time to work, Treating Lupus with Anti-Malarial Drugs Johns Hopkins Lupus. Hydroxychloroquine neuropathyPrilosec and plaquenil interactions The usual starting dose of Plaquenil is 200 mg twice a day or 400 mg once a day, administered orally, in people weighing 80 kg or more. The usual dosage works for most people who take Plaquenil, but it is possible to increase or decrease the dose based on individual needs. It's important to watch for possible side effects and toxicity. Taking Plaquenil for Rheumatoid Arthritis. Hydroxychloroquine Side Effects, Dosage, Uses, and More. Hydroxychloroquine - Side Effects, Dosage, Interactions.. Hydroxychloroquine is a relatively safe medication but it is recommended to have regular monitoring by an ophthalmologist eye doctor while taking this drug. Before you begin taking Plaquenil, tell you doctor your complete medical history including any eye problems that may have come from other aminoquinolines other antimalarial drugs such. Take hydroxychloroquine for the full prescribed length of time for malaria. Your symptoms may improve before the infection is completely cleared. When treating lupus or arthritis, tell your doctor if your symptoms do not improve after 6 months of treatment. Before taking this medicine. You should not use hydroxychloroquine if you are allergic. Children should not take hydroxychloroquine for long-term therapy. Keep all appointments with your doctor and the laboratory. Your doctor may order certain lab tests to check your response to hydroxychloroquine. If you are taking hydroxychloroquine for a long period of time, your doctor will recommend frequent eye exams.