Her rheumatologist instructed her to undergo a baseline ocular examination prior to initiating Plaquenil (hydroxychloroquine, Sanofi-Aventis) therapy. Toxic maculopathy associated with chloroquine use was first documented in the literature five decades ago.1 In the United States, Plaquenil––an analog to chloroquine––is used to treat a variety of conditions, including rheumatoid arthritis, lupus and several distinct inflammatory disorders. Although the incidence of macular toxicity is infrequent with Plaquenil use (at a dosage of 200mg or 400mg q.d.), its visual impact can be devastating. Plaquenil antinflammatory Plaquenil and blood pressure Effect of plaquenil on free light chains A 57-year-old female presented to the Ophthalmology clinic at UIHC complaining bilateral central photopsias for the past two years. She suffered from Sjogren syndrome and inflammatory arthritis and was currently treated with prednisone and methotrexate. She was previously treated with hydroxychloroquine Plaquenil 200mg bid 6.5mg/kg for 10 years, which was stopped one year prior to. Hydroxychloroquine. AOA the National Medical Honor Society and a Diplomat of the American Board of Medical Examiners. Recent posts. 27 October 2019 In Surgery Aberrometry. 19 August 2019 What is Minimally Invasive Glaucoma Surgery or MIGS? 19 July 2019 What is a Punctal Plug? Hydroxychloroquine is a well-tolerated medication for various rheumatologic and dermatologic conditions. Its main side effects are gastrointestinal upset, skin rash, headache, and ocular toxicity1. Within the eye, hydroxychloroquine can adversely impact the cornea, ciliary body, and retina1 Initially, central visual acuity may be unaffected, but the patient may notice related paracentral scotomas that often interfere with reading. The associated classic retinal toxicity is described as a bull’s eye maculopathy (ring of depigmented retinal pigment epithelium that spares the foveal area). Hydroxychloroquine aoa How to Succeed in Plaquenil Screenings, What can Hydroxychloroquine Plaquenil do to my eyes? Can plaquenil affect menstruationHow commonly is hydroxychloroquine used for autoimmuneDoes allopurinol interact with plaquenilIs plaquenil used to treat sjogren& 39Can you take plaquenil with flagyl Hydroxychloroquine is used in the treatment of juvenile idiopathic arthritis, rheumatoid arthritis, systemic and discoid lupus, juvenile dermatomyositis and maybe sometimes be helpful in sarcoidosis. In lupus and rheumatoid arthritis the response to treatment may be slow but if there is no clinical improvement within 6 Guidelines for Hydroxychloroquine Plaquenil Treatment. Hydroxychloroquine toxicity - EyeWiki. New Plaquenil Guidelines. Sjogren's syndrome is an autoimmune means that your immune system attacks parts of your own body by mistake. In Sjogren's syndrome, it attacks the glands that make tears and saliva. Factors for toxicity related to hydroxychloroquine use. BACKGROUND 1 Hydroxychloroquine HCQ, brand name Plaquenil is commonly used for the long-term 2 management of a variety of chronic rheumatic diseases including systemic lupus erythematosus 3 and rheumatoid arthritis. A range of potential toxicities related to HCQ use have been reported AOA Diabetic Eye Examination Report ©This form was developed by the Ohio Optometric Association and The Ohio State University College of Optometry through support from the NIH Healthy Vision 2010 Awards Program and an AOA Healthy Eyes Healthy People Grant.