It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Malaria is spread by mosquitoes, which transmit the parasites that cause the infection, usually in tropical and subtropical parts of the world. Effect of chloroquine on sle Hydroxychloroquine retinopathy mechanism Plaquenil and ldn A controlled, double blind, parallel group, long term study of hydroxychloroquine sulphate in the treatment of rheumatoid arthritis, comparing daily doses of 200 mg and 400 mg, is described. The trial involved 54 patients with moderate disease activity who had not previously received antimalarial drugs. For the treatment of RA, hydroxychloroquine is typically taken by mouth once daily at 200-400 mg, although it can be taken at a higher dose. A loading dose of 1,200 mg daily, given for 6 weeks may decrease the time to clinical response. However, experts debate that this higher dosage may increase the risk of toxicity. Rated Plaquenil for Rheumatoid Arthritis Report. After taking for 200 mg a day for about 2-3 months, my RA pains were much less. However i began suffering from vertigo and dizzy spells! For example, it may be combined with an antibiotic to treat chronic Q-fever, which humans usually catch from farm animals or raw milk. Plaquenil is used to treat other types of infections too. Plaquenil dose for rheumatoid arthritis RA and Hydroxychloroquine How Effective is it for Rheumatoid Arthritis., Treatments for Rheumatoid Arthritis Basic description of chloroquinePlaquenil and shoulder painHydroxychloroquine normal dose rangeChloroquine drug side effectsChloroquine methemoglobin The recommended starting Plaquenil dose for rheumatoid arthritis treatment is 400 to 600 mg daily. In some people, the starting dose may need to be temporarily reduced for a week or so if bothersome side effects occur. Taking Plaquenil for Various Conditions and Treatment Tips. Plaquenil Reviews Everyday Health. Long-Term Side Effects of Plaquenil for Rheumatoid Arthritis.. My rheumatologist put me on prednisolone reduced doses over in 3 months until the methotrexate starts working once a week of 15mg for 2 weeks, 20mg once a week indefinitely. Plaquenil 300mg daily. I also take Vit D daily and 5mg folic acid once a week plus curcumin and fish oil I have been taking it all with breakfast for the last 8 days. Jan 03, 2020 Weight based dosage in adults and pediatric patients 13 mg/kg 10 mg/kg base, not to exceed 800 mg 620 mg base followed by 6.5 mg/kg 5 mg/kg base, not to exceed 400 mg 310 mg base, at 6 hours, 24 hours and 48 hours after the initial dose. PLAQUENIL film-coated tablets cannot be divided, therefore they should not be used to treat patients who weigh less than 31 kg. Adult dosing ranges from 200 mg or 400 mg per day 6.5mg/kg. In some cases, higher doses can be used. It is recommended one tablet twice daily if taking more than one tablet. It is recommended to be taken with food.