In Sjögren’s, Plaquenil is used to treat many symptoms of Sjögren’s including fatigue, joint symptoms of arthritis and arthralgias (joint pain), dry mouth and dry eyes. Similar to its use in systemic lupus erythematosus, many clinicians feel that it is useful in reducing general Sjögren’s “disease activity.” One of the reasons that physicians feel comfortable in prescribing Plaquenil is its low risk to benefit ratio. Side effectsof chloroquine Drugs used to treat chloroquine resistant malaria Hydroxychloroquine lupus What are the long term side effects of plaquenil Obtain a baseline eye exam within the first year of starting hydroxychloroquine to document any complicating eye problem. Annual screening beginning after 5 years of use. Sooner if there are major risk factors. Check the dose of hydroxychloroquine based on your weight at your doctor’s appointment. While side effects of corticosteroids are usually to blame, there is also the possibility of ocular damage associated with long-term use of the antimalarial drugs hydroxychloroquine brand name Plaquenil® and chloroquine. Improved vision screening tests and updated dosing guidelines are key to avoiding such complications. Some of the medications used to treat rheumatoid arthritis, such as prednisone a corticosteroid and Plaquenil hydroxychloroquine, can actually trigger eye problems. “Plaquenil, on rare. As with any medication, allergic reactions including skin rashes and non-allergic reactions can occur. This means that the side effects of Plaquenil are mild and infrequent compared with its potential benefits. Eye problems on hydroxychloroquine Hydroxychloroquine Plaquenil, Protecting your eyesight when taking Plaquenil Lupus. Hydroxychloroquine interaction with gabapentinPlaquenil gridDiscontinuing plaquenil Hearing problems, such as ringing or ticking in the ears, or hearing changes Plaquenil may have toxic effects on your inner ear Loss of balance, coordination, room spinning, or other vertigo. Plaquenil Hydroxychloroquine - Side Effects, Dosage.. RA and Your Eyes Complications Rheumatoid Arthritis.. The Risk of Retinal Toxicity with Plaquenil. Hydroxychloroquine Plaquenil is used to treat malaria, lupus, and rheumatoid arthritis. Learn about side effects, warnings, dosage, and more. If you do, your risk of eye problems will. Plaquenil and Your Eyes In some people, Plaquenil can cause a condition called hydroxychloroquine retinopathy, often referred to as bulls-eye maculopathy. The condition sometimes resembles a target, or bulls-eye ring, on the retina surrounding the macula. Beyond Plaquenil Other Drugs, Other Problems. If you’re looking for a comprehensive assessment of drug reactions that relate to the eye, Dr. Fraunfelder and his father, Frederick T. “Fritz” Fraunfelder, MD, along with Wiley A. Chambers, MD, literally wrote the book. 3 “So many drugs can cause ocular side effects that if you’re trying to make a point about which drugs to watch out.