The patient had been on Amiodarone therapy for several years. These deposits occur in various levels of the cornea. Two months prior to this routine follow up, the patient's primary care doctor made a change in the patient's cardiac medications which included the removal of amiodarone from his medication regimen. Corneal verticillata, also called vortex keratopathy, are one type of corneal deposits. Aralen patient teaching Chloroquine phosphate flukes Natural medicine comparable to hydroxychloroquine Taking Hydroxychloroquine develop toxicity2 It’s rare for side effects to occur with Plaquenil if the medication is dosed properly Side effects Blurred vision, bull’s eye maculopathy, scotoma, vortex keratopathy, headache, accommodative dysfunction, whitening of eyelashes, phototoxicity3 Toxicity from hydroxychloroquine may be seen in two distinct areas of the eye the cornea and the macula. The cornea may become affected relatively commonly by an innocuous cornea verticillata or vortex keratopathy and is characterized by whorl-like corneal epithelial deposits. These changes bear no relationship to dosage and are usually reversible on cessation of hydroxychloroquine. Hydroxychloroquine is used in the U. S. for treating inflammatory disorders such as systemic lupus erythematosus, rheumatoid. “The cornea may become affected by an innocuous vortex keratopathy. The opacities branch out from a central whorl, usually across the inferior cornea. Verticillata are readily recognizable by their distinct appearance as fine, golden-brown or gray opacities that are almost always bilateral. Vortex keratopathy hydroxychloroquine Cornea Verticillata - an overview ScienceDirect Topics, Hydroxychloroquine - Wikipedia Can i buy chloroquine over the counterChloroquine resistance countriesCheap aralen 250 The long-term administration of hydroxychloroquine HCQ sulfate is well known to be associated with AE, such as vortex keratopathy and in particular the often irreversiblenih.gov as convulsion-like syndromes and impaired consciousness. 54 MRI revealed abnormal signal intensity on T2-weighted images in all cases. Consciousness Disorder & Vortex Keratopathy Causes & Reasons.. Newer technology advised for screening patients taking.. Corneal verticillata - American Academy of Ophthalmology. Cornea verticillata, also called vortex keratopathy or whorl keratopathy, is a condition characterised by corneal deposits at the level of the basal epithelium forming a faint golden-brown whorl pattern. It is seen in Fabry disease or in case of prolonged amiodarone intake. Causes Amiodarone Fabry’s disease Chloroquine Hydroxychloroquine Indomethacin Phenothiazines etc. Other signs are Pancreatitis, Lupus Enteropathy, Hepatitis and Hepatomegaly 5. Systemic Fever, Malaise/Fatigue, Lymphadenopathy, Weight loss 6.fidanoski.ca The long-term administration of hydroxychloroquine HCQ sulfate is well known to be associated with AE, such as vortex keratopathy and in particular the often irreversiblenih.gov keratopathy and maculopathy. In 1 case related to perhexiline maleate, papilledema appearing concurrently with the vortex keratopathy and considered drug related resulted in significant visual acuity loss that did not completely reverse after withdrawal of the drug. 24 Besides asymptomatic vortex keratopathy, retinal toxicity—including macular and peripheral retina.