Begin 1-2 days before travel, daily during travel, and for 7 days after leaving. 1250 mg orally as a single dose Use: For treatment of mild to moderate acute malaria due to mefloquine-susceptible strains of Plasmodium falciparum (both chloroquine-susceptible and -resistant strains) or P vivax US CDC Recommendations: 750 mg orally as initial dose, followed by 500 mg orally 6 to 12 hours after initial dose Comments: -Recommended for treatment of uncomplicated malaria due to chloroquine-resistant (or unknown resistance) P falciparum (or species not identified) if other preferred regimens cannot be used; not recommended if infection was acquired in Southeast Asia (due to resistance) -With (primaquine or tafenoquine [Krintafel]), recommended for treatment of uncomplicated malaria due to chloroquine-resistant P vivax; this drug should be used alone during pregnancy. Plaquenil method of action Plaquenil eye damage Acute Malaria Infections. Indicated for the treatment of mild-to-moderate acute malaria caused by mefloquine-susceptible strains of P. falciparum both chloroquine-susceptible and resistant strains or by Plasmodium vivax Mefloquine can pass into breast milk and may harm a nursing baby. Tell your doctor if you are breast-feeding a baby. Mefloquine should not be used to treat malaria in a child younger than 6 months without a doctor's advice. Mefloquine should not be used to prevent malaria in a child who weighs less than 44 pounds. Mefloquine is used as a treatment for chloroquine -sensitive or resistant Plasmodium falciparum malaria, and is deemed a reasonable alternative for uncomplicated chloroquine-resistant Plasmodium vivax malaria. It is one of several drugs recommended by the United States' Centers for Disease Control and Prevention. 250 mg orally once a week Comments: -This drug should be taken on the same day of each week, preferably after the main meal. -After IV artesunate, for severe malaria (if other options are not available); if needed, as interim therapy for severe malaria until IV artesunate arrives (if other options are not available) -Current guidelines should be consulted for additional information. Mefloquine lariam and chloroquine Lariam Mefloquine Uses, Dosage, Side Effects., Mefloquine Uses, Side Effects & Warnings - Does plaquenil help with allergies Mefloquine comes as a tablet to take by mouth. Always take mefloquine with food preferably your main meal and at least 8 ounces 240 milliliters of water. If you are taking mefloquine to prevent malaria, you will probably take it once a week on the same day each week. Mefloquine MedlinePlus Drug Information. Mefloquine - Wikipedia. Mefloquine Dosage Guide with Precautions -. For travel to areas where chloroquine resistance is present, mefloquine is the only medication recommended for malaria prophylaxis during pregnancy. Studies of mefloquine use during pregnancy have found no indication of adverse effects on the fetus. Mefloquine is a medicine used to treat malaria, a disease caused by parasites. This medicine works by interfering with the growth of parasites in the red blood cells of the human body. Mefloquine, like chloroquine and quinine, is a blood schizonticidal agent and is active against the intraerythrocytic stages of parasite development. Similar to chloroquine and quinine, mefloquine appears to interfere with the parasite's ability to metabolize and utilize erythrocyte hemoglobin.