It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Plaquenil history Chloroquine concentration lysosome Can plaquenil cause loss of hearing Plaquenil back pain and headache Brittle bone disease is caused by a defect in collagen production. Collagen protein is vital in supporting the body. Of the several types of collagen we have, Type I is the most abundant and found in the bones, teeth, ligaments, and eye sclera. Brittle bone disease affects both men and women and people of all races. Along with its needed effects, hydroxychloroquine the active ingredient contained in Plaquenil may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine Brittle bone disease type 2 most severe form Lethal – Most, but not all, die in early childhood. Severe deformity is common, and infants generally do not survive long after birth. Brittle bone disease type 3 severe form Progressive deforming – Decreased life expectancy. It is characterized by bones that fracture easily and also bend. Today, it is used to treat rheumatoid arthritis, some symptoms of lupus, childhood arthritis (or juvenile idiopathic arthritis) and other autoimmune diseases. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Does plaquenil give you brittle bones Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses, Plaquenil Side Effects Common, Severe, Long Term - Cost of chloroquine and proguanilIs mefloquine the same as chloroquineDrug reaction with acyclovir and sucralfate and hydroxychloroquineWhich autoimmune not treat with plaquenilChloroquine phosphate for lupus This is what goes on in healthy pre-menopausal women who have optimal hormone levels. Low levels of the hormones estrogen and progesterone in post-menopausal women cause bone to be broken down more quickly than it can be replaced. As a result, such women often have weak, brittle bones and higher susceptibility to breaks and fractures. Bone drug Prolia can lead to fractures and bone death. Brittle bone disease causes, symptoms, life expectancy and.. Rx Side Effects New Plaquenil Guidelines and More - American.. In rare cases, Plaquenil can cause cardiomyopathy, a chronic disease of the heart muscle. If you're taking Plaquenil for an autoimmune condition, your symptoms should begin to improve after a few. It worked wonders for that. For that reason I am satisfied with plaquenil for what I took it for. Took about 5-6 months to see full effect. Since reducing the dose from 400mg to 200mg 4 months ago I do feel some of this pain returning You win some, you lose some! M 49 1 years 400mg day 7/25/2019 Email 1 lupus Plaquenil can make you. So you still have the bottle of plaquenil and are not ready to start taking it? Besides what I have already written to you, the only advice I can give is to consider all the ways this disease impacts your life and weigh that against the possible side effects. Also consider the prognosis of the condition.