It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Plaquenil weight gain loss Plaquenil toxicity symptoms liver It is not well understood how Plaquenil helps treat autoimmune diseases like lupus and many types of arthritis. It is thought that Plaquenil interferes with how cells in the immune system communicate with each other. This study is created by eHealthMe based on reports of 57,706 people who have side effects when taking Plaquenil from Food and Drug Administration FDA, and is updated regularly. On eHealthMe, you can evaluate side effects and drug interactions from 16 million FDA reports. The results are personalized to your gender and age 0-99+. Immune system disorder is found among people who take Plaquenil, especially for people who are female, 50-59 old, have been taking the drug for 5 - 10 years, also take medication Enbrel, and have Pain Today, it is used to treat rheumatoid arthritis, some symptoms of lupus, childhood arthritis (or juvenile idiopathic arthritis) and other autoimmune diseases. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Does plaquenil affect immune system Plaquenil side effects" Lupus Community - Support Group, Will you have Immunodeficiency disorders with Plaquenil. Plaquenil and hair thinningHydroxychloroquine azithromycinPlaquenil and grapefruitDoes plaquenil work on osteoarthritis Now I am only on paquinil - it has been 3 years now and I am feeling fantastic with no side effects and my eyes are perfect. I feel completely normal and almost forget. It does take months in the beginning but stuck with it. The fact that it is not damaging to your immune system is a HUGE PLUS. Protect and build your immune ! Reasonably Well Plaquenil FAQ. Will you have Immune system disorder with Plaquenil - eHealthMe. What does Plaquenil do? -. Topsy, hi. Hydroxychloroquine Plaquenil is a first-tier med meaning lightest taken for lupus where there's no major organ involvement; it's also used for Sjogren's syndrome, and I think also for mild RA. It doesn't suppress your immune system good news. Any one have any experience or info regarding pre-existing precancerous conditions and the effects of Plaquenil on the immune system. I see so much info on the net where some says that Plaquenil has very mild effect on immune system except for eye issues --- Other info says it is an immunosuppressant. Hi everyone, I am coming down with something and I dont feel very good. I have not had a cold or the flu in years and years. And I was wondereing if my being on he plaquenil has made my immune system less able to fight off every bug that comes my way.