Hydroxychloroquine is available as the brand-name drug Plaquenil. Generic drugs usually cost less than the brand-name version. Hydroxychloroquine may be used as part of a combination therapy. Chloroquine mechanism of action lupus Plaquenil medication oral pigmentation Plaquenil and coq10 Plaquenil hydroxychloroquine is considered an older DMARD disease modifying anti-rheumatic drug. Plaquenil was actually first classified as an antimalarial drug, but it is also used to treat certain rheumatic and autoimmune conditions which are unrelated to malaria. Generally, Plaquenil is a treatment option as monotherapy used alone for mild rheumatoid arthritis or as combination. Yes I have had a positive Ana test in 2003 0 and just this year had two negative Ana, one while on plaquenil and one after being off plaquenil for 3weeks. Maybe if you are on medication that is what is causing the ana to be negative. Hydroxychloroquine Plaquenil is considered a disease-modifying anti-rheumatic drug DMARD. It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Hydroxychloroquine is used to treat lupus erythematosus and rheumatoid arthritis. It isn’t fully understood how this drug works to treat lupus erythematosus or rheumatoid arthritis. That means you may need to take it with other drugs. It treats malaria by killing the parasites that cause the disease. Ana and plaquenil Treating Lupus with Anti-Malarial Drugs Johns Hopkins Lupus., Can ANA go away & Lupus Stay? - Lupus - MedHelp Hydroxychloroquine eye exam frequency What is Plaquenil Hydroxychloroquine? Plaquenil is most known for its original purpose treating and preventing malaria. Malaria is a disease caused by parasites that can enter the body through a mosquito bite. The essential ingredient, known as quinine, is derived from the bark of the cinchona plant. Plaquenil Hydroxychloroquine for Lupus - LupusCorner. Hydroxychloroquine Plaquenil. How is plaquenil hydroxychloroquine used to treat lupus?. Vanessa, whatever you decide is the best for you is key and how you feel in yourself, give the plaquenil a bit longer if you are not reacting as it does take a while to get into the system but if you are unhappy about it, discuss the concerns you have with the doctor and take it from there. ANA titers go up and down during the course of the disease, and a high or low titer does not necessarily mean the disease is more or less active. Therefore, it is not always possible to determine the activity of the disease from the ANA titer. A titer above is usually considered positive. Hydroxychloroquine is a DMARD. The brand name is Plaquenil. What does Plaquenil do? Plaquenil relieves pain and swelling and prevents damage to joints. How long does Plaquenil take to work? Plaquenil works very slowly. In 1 to 3 months you should start to feel better. You may continue to get better for up to 1 year.