Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Prozac and plaquenil Ocular effects of chloroquine therapy Hydroxychloroquine Plaquenil is considered a disease-modifying anti-rheumatic drug DMARD. It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except. To get a Lupus diganosis you need to have 4 or more of 11 Lupus criteria, within a 5 year period. A lot of people have less than 4, or as in my case, more than 4 but spread out over much more than 5 years. So it's very possible for plaquenil to do good without you being considered to have Lupus. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Plaquenil menstruation disturbance Hydroxychloroquine cardiotoxicity presenting as a rapidly., What Conditions does Plaquenil Treat? - WebMD Plaquenil helped my fatigueHow does plaquenil work for sjogren& 39Painful muscle spasms from plaquenil It's very rare and only occurs in a tiny fraction of people who take Plaquenil in large doses for many years like 20. The chances of it harming any other part of your eye are 0%. Plaquenil is a great lupus medication because unlike the other lupus meds, it doesn't suppress our already-compromised. Before and after diagnosis? - WebMD Message Boards. Plaquenil -. Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses. Apr 10, 2019 Plaquenil is sometimes given only once per week. Choose the same day each week to take this medicine if you are on a weekly dosing schedule. Take Plaquenil with a meal or a glass of milk. To prevent malaria Start taking Plaquenil 2 weeks before entering an area where malaria is common. Continue taking the medicine regularly during your stay. Asian patients, ocular disease, visual disturbance Severe and irreversible retinal damage has been reported with the use of hydroxychloroquine. Risk factors for retinal damage include daily doses more than 6.5 mg/kg 5 mg/kg base of actual body weight, durations of use greater than 5 years, subnormal glomerular filtration, use of concomitant drugs such as tamoxifen, and concurrent macular disease. With Plaquenil, however, the most commonly prescribed anti-malarial, this sort of damage occurs only in 1 out of 5,000 people who take the drug for five years or more. For this reason though, it is important that you see an ophthalmologist for an exam before starting to take an anti-malarial medication for your lupus.