Plaquenil induced cardiomyopathy

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  1. Drummer New Member

    Plaquenil induced cardiomyopathy


    She had been taking hydroxychloroquine as a disease-modifying agent for about 15 years. A transthoracic echocardiogram showed reduced left ventricular function with an ejection fraction of 35% (A, Online Video 1).

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    Genetic predisposition for HCQ‐induced cardiomyopathy was first proposed in a set of twin sisters who both suffered from SLE. 9 Chatre et al. described a case of a 61‐year‐old woman whose diagnosis of α‐galactosidase A deficiency was unmasked by chronic HCQ treatment. 10 Because Fabry disease and other lysosomal storage disorders, such. Soong TR, Barouch LA, Champion HC et al 2007 New clinical and ultrastructural findings in hydroxychloroquine-induced cardiomyopathy—a report of 2 cases. Hydroxychloroquine is used in the treatment of various rheumatic conditions including systemic lupus erythematous. Hydroxychloroquine induced myopathy is rare adverse reaction but symptoms are usually recover after discontinuation of the drug. Here we report a case of woman with systemic lupus erythematosus who presented with myopathy after eight months treatment with hydroxychloroquine.

    Periodic-acid Schiff staining showed glycogen deposition in myocyte cytoplasm. Subsequent coronary angiography revealed normal coronary arteries. Hematoxylin and eosin staining revealed myocyte vacuolization (B).

    Plaquenil induced cardiomyopathy

    A Rare but Reversible Cause of Myopathy Hydroxychloroquine., Hydroxychloroquine-induced cardiomyopathy in a patient with.

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  7. Drug-induced cardiotoxicity including chemotherapy-induced cardiotoxicity remains an important cause of heart disease and heart failure.1, 2, 3 Cardiomyopathy from cancer chemotherapy is well recognized as a drug-induced complication but the cardiotoxicity from other drugs is not well described.2, 3 Chloroquine CQ and hydroxychloroquine HCQ are 4-aminoquinolines 4 at one time commonly used.

    • Hydroxychloroquine-Induced Cardiomyopathy Case Report, Pathophysiology..
    • A Rare but Reversible Cause of Myopathy..
    • Drug-induced myopathies - UpToDate.

    This article is from June 2011 and may contain outdated material. Download PDF. Many systemic medications may cause retinal toxicity. One such commonly used medication for dermatologic and rheumatologic inflammatory conditions is hydroxychloroquine Plaquenil, a chloroquine derivative. In rare cases, Plaquenil can cause cardiomyopathy, a chronic disease of the heart muscle. If you're taking Plaquenil for an autoimmune condition, your symptoms should begin to improve after a few. Cardiac disorders Cardiomyopathy which may result in cardiac failure and in some cases a fatal outcome see WARNINGS and OVERDOSAGE. PLAQUENIL prolongs the QT interval. Ventricular arrhythmias and torsade de pointes have been reported in patients taking PLAQUENIL see OVERDOSAGE and DRUG INTERACTIONS.

     
  8. jeg Guest

    Hydroxychloroquine is a quinoline medicine used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Will you have Stress and anxiety with Plaquenil - eHealthMe Plaquenil oral Reviews and User Ratings Effectiveness, Ease of Use. Plaquenil and Depression/Anxiety - Symptoms and Medical.
     
  9. Liveword Well-Known Member

    Taking Plaquenil for Rheumatoid Arthritis Plaquenil is a DMARD which has been prescribed for years to treat rheumatoid arthritis, lupus, juvenile rheumatoid arthritis, and other autoimmune diseases. When the first biologic DMARD received FDA-approval in 1998, and as other biologics followed in subsequent years, it appeared as though Plaquenil would become less prescribed.

    Long-Term Side Effects of Plaquenil for Rheumatoid Arthritis.
     
  10. Vitalik Well-Known Member

    Hydroxychloroquine Plaquenil Hydroxychloroquine Plaquenil is considered a disease-modifying anti-rheumatic drug DMARD. It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria.

    Malaria Treatment and Prevention Everyday Health